I was on a business trip with a bunch of engineers
We flew to Mansfield, OH for a factory tour and pump hydraulics school. One of the fellows was a shooter and a P.E. Interesting fellow, a pilot, former farmer, crop duster, med-flight pilot, and reloader. He even has a FFL and Class III license. We got to talking and he confessed of a bad shooting bench mistake he once made. He actually fired a 6.5 Grendel out of his .22-250 bolt gun. I checked and he still had both eyes and all digits! The gun however was not so good. It wrecked the barrel threads and bolt lugs.
I asked him where the bullet went? He told me "out the end of the barrel!" but I bet it was unusually long for caliber! LOL
I was told of another fellow who mixed pistol powders on a load bench and shot a .300 Wby. case filled with pistol powder. It almost killed him, blowing the rifle in half inches from his face. The bolt body actually flew through his cheek. There are some very important reasons you maintain safety practices and prevent complacency. Just because you have been doing something 40 years does not mean you can take shortcuts or let your guard down.